Pregnancy Outcomes and Reproductive Counseling in Women with Triple X Syndrome

Trisomy X is a sex chromosomal abnormality, with an incidence of about 1 in 1,000 female births. [1] In this article, we discuss five women with Triple X Syndrome and issues surrounding pregnancy outcomes and recurrence risk in their pregnancies. The cases highlight the variability in reproductive experiences, ranging from recurrent pregnancy losses to successful deliveries. Triple X is being commonly encountered at prenatal diagnosis due to the increasing use of noninvasive prenatal screening in obstetric practice and we feel that counseling is most of the time inadequate for the prospective parents to take informed decision, leading to termination of the pregnancy. This article aims to provide information regarding pregnancy-related outcomes mainly but indirectly provides information regarding mental and physical well-being of these women and hence may provide assurance to the prospective parents.