Ryanodane diterpenes: occurrence, structural diversity, bioactivities, and synthesis

Key Points

• Identifying key bioactivities of natural ryanodane diterpenes reveals their potential therapeutic uses in modern medicine.
• The study includes a detailed examination of 135 ryanodane diterpenes sourced from a range of botanical species, emphasizing their unique structural traits.
• The review covers chemical synthesis methods that can facilitate the production of ryanodane diterpenes for research and pharmaceutical applications.
• Understanding the structural diversity of these diterpenes may aid in the discovery of novel compounds with significant bioactivities.