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October 1, 2025

Supplemental Table 4 from Immune Activation Signatures Associated with Fatigue in Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy

Howard L. Li Soren Charmsaz Mari Nakazawa Stephanie Alden Madelena Brancati James M. Leatherman Ervin Griffin Hua‐Ling Tsai Nicole Groß Christopher J. Thoburn Alexei Hernandez Erin M. Coyne Sarah M. Shin Royce P. Lee Evan J. Lipson Burles A. Johnson Aliyah Pabani Yasser Ged Marina Baretti Julie R. Brahmer Jean Hoffman‐Censits Tanguy Y. Seiwert Daniel J. Zabransky Jennifer N. Durham Elizabeth M. Jaffee G. Scott Chandler Brittany L. Adler Won Jin Ho Chester Kao Mark Yarchoan

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Key Points

Significant differences in cytokines were found between fatigued and non-fatigued cancer patients undergoing therapy.
The analysis revealed distinct cytokine profiles associated with fatigue, underscoring immune activation's role.
Cytokines were assessed for fold change differences, providing insights into the immune response in fatigued patients.
These findings may guide future interventions to manage fatigue in cancer patients receiving treatment.

Implication

This analysis highlights significant cytokines linked to fatigue in cancer patients, suggesting immune factors at play.

Abstract

Supplemental Table 4 shows all significant cytokines for differences in fold change between fatigue and non-fatigued patients.

Discussion

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Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a21836 https://doi.org/10.1158/2767-9764.30256029

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplemental Table 5 from Immune Activation Signatures Associated with Fatigue in Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy2025
2Supplemental Table 3 from Immune Activation Signatures Associated with Fatigue in Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy2025
3Supplemental Table 6 from Immune Activation Signatures Associated with Fatigue in Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy2025
4Supplemental Table 2 from Immune Activation Signatures Associated with Fatigue in Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy2025
5Supplemental Figure 2 from Immune Activation Signatures Associated with Fatigue in Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy2025