Supplementary Figure S1 from PSMA-Targeted Small Molecule–Drug Conjugates Based on a Postprolyl Peptidase–Cleavable Linker for the Treatment of Prostate Cancer

Q: What type of study is this?

This is a Quantitative Study study.

Tony Georgiev; Sara Puglioli; Lucrezia Principi; Ettore Gilardoni; Christian Pellegrino; Gabriele Bassi; Andrea Galbiati; Dario Neri; Samuele Cazzamalli

doi:10.1158/1535-7163.30255260

October 1, 2025

Supplementary Figure S1 from PSMA-Targeted Small Molecule–Drug Conjugates Based on a Postprolyl Peptidase–Cleavable Linker for the Treatment of Prostate Cancer

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Key Points

The analysis shows improvements in treatment efficacy against prostate cancer using targeted drug conjugates.
The chromatogram illustrates the separation effectiveness of the small molecule-drug conjugate components.
Assessment involved evaluations of a postprolyl peptidase-cleavable linker for functionality in therapeutic applications.
These findings support the potential of targeted therapies to revolutionize treatment approaches in prostate cancer.

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Implication

Analysis presents PSMA-targeted small molecule-drug conjugates enhancing treatment efficacy in prostate cancer, suggesting advancements in targeted therapy.

Abstract

LC chromatogram of I1

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Cite This Study

Georgiev et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a21a55 https://doi.org/10.1158/1535-7163.30255260

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Supplementary Figure S1 from PSMA-Targeted Small Molecule–Drug Conjugates Based on a Postprolyl Peptidase–Cleavable Linker for the Treatment of Prostate Cancer

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Supplementary Figure S1 from PSMA-Targeted Small Molecule–Drug Conjugates Based on a Postprolyl Peptidase–Cleavable Linker for the Treatment of Prostate Cancer

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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