Early Assessment of Rheumatoid Arthritis Using the Nørgaard Radiographic Method and Rheumatoid Factor Testing

Background: This comparative study was conducted between July 25 and December 31, 2022, at Abusurra Hospital and Zawia Teaching Hospital in Libya to assess the efficacy of the Norgaard radiographic method versus laboratory analysis in the early detection of rheumatoid arthritis. A total of 64 patients of varying ages and clinical presentations were examined using both diagnostic approaches. Material and Methods: Radiographic assessment was performed using the Norgaard method, which focuses on early joint deformities, particularly in the metacarpophalangeal and proximal interphalangeal joints, while blood samples were collected for serological testing, including markers such as Rheumatoid Factor (RF). Results showed that 3 cases were identified simultaneously by both methods, 12 cases were exclusively detected using the Norgaard radiographs, and 8 cases were identified through laboratory analysis alone. These findings suggest that the Norgaard method may offer superior sensitivity in the early diagnosis of rheumatoid inflammation, especially when radiographic signs precede serological changes. However, the combination of both methods may enhance diagnostic confidence and reduce false negatives in ambiguous clinical cases. Conclusion:. We recommend that future research include broader screening of suspected rheumatoid arthritis cases in outpatient settings using both radiological and laboratory approaches. Emphasis should be placed on standardizing radiographic criteria and correlating imaging findings with serological profiles and clinical symptoms to establish a more comprehensive diagnostic framework.