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October 1, 2025

Figure S4 from ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance

Ting Zeng Xiao Ding Zhu Wei Di Wu Hong Yi Wei Huang Shan-Shan Lu Zheng-Zheng Yu Qi Wen Yun‐Xi Peng Li Yuan Zhi‐Qiang Xiao Jinwu Peng

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Key Points

ANXA1 significantly improves radioresistance in nasopharyngeal carcinoma cells.
EGFR binding and stabilization by ANXA1 is critical in enhancing NPC cell survival under radiation.
In vitro studies reveal that ANXA1 plays a pivotal role in NPC cell responses to radio treatment.
Understanding ANXA1's mechanism may lead to better strategies in targeting radioresistance in cancer therapies.

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Implication

Figure shows ANXA1 binds and stabilizes EGFR, improving NPC radioresistance, highlighting its role in cancer treatment.

Abstract

Figure S4. ANXA1 increases in vitro NPC cell radioresistance via binding and stabilizing EGFR

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Cite This Study

Zeng et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a21ac6 https://doi.org/10.1158/1535-7163.30255056

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S3 from ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance2025
2Figure S6 from ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance2025
3Figure S7 from ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance2025
4Figure S2 from ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance2025
5Figure S5 from ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance2025

Table S1 from ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance2025
Data from ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance2025
Figure S1 from ANXA1 Binds and Stabilizes EGFR to Promote Nasopharyngeal Carcinoma Radioresistance2025