Table S3 from Tumor-Derived CCL16 Normalizes Tumor Vasculature through Macrophage ICAM-1 Receptor and Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Q: What type of study is this?

This is a Quantitative Study study.

Kunling Chen; Huolun Feng; Y H Zhang; Jingyuan Pei; Yuyan Xu; Xiangxu Wei; Zhuohao Chen; Zhoubin Feng; Lei Cai; Yong Li; Liang Zhao; Mingxin Pan

doi:10.1158/0008-5472.30254911

October 1, 2025

Table S3 from Tumor-Derived CCL16 Normalizes Tumor Vasculature through Macrophage ICAM-1 Receptor and Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

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Key Points

Tumor-derived ccl16 improves tumor vasculature, enhancing immunotherapy response in hepatocellular carcinoma.
The increase in immunotherapy efficacy involves the macrophage icam-1 receptor pathway, revealing a critical relationship.
Analysis using fluorochrome-conjugated antibodies in flow cytometry examines interactions within the tumor microenvironment.
Findings may lead to new therapeutic strategies targeting tumor vasculature for better cancer treatment.

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Implication

Observational analysis shows tumor-derived ccl16 normalizes tumor vasculature in hepatocellular carcinoma, suggesting it may enhance immunotherapy efficacy.

Abstract

Fluorochrome-conjugated antibodies in flow cytometry

Discussion

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Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a21b1a https://doi.org/10.1158/0008-5472.30254911

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Table S3 from Tumor-Derived CCL16 Normalizes Tumor Vasculature through Macrophage ICAM-1 Receptor and Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Table S3 from Tumor-Derived CCL16 Normalizes Tumor Vasculature through Macrophage ICAM-1 Receptor and Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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