This research demonstrates synergistic effects of curcuma longa extract and resveratrol on colorectal cancer, indicating significant KRAS downregulation in female rats.
Key Points
Treatment with curcuma longa and resveratrol significantly reduced KRAS expression and improved tissue integrity in rats with colorectal cancer.
Rats receiving combined treatment showed the lowest KRAS expression levels and near-normal tissue architecture after 16 weeks.
Colorectal cancer was induced using DMH in female albino rats, with various treatment groups established to evaluate protective effects.
These findings suggest a promising role for curcuma longa and resveratrol as complementary agents in colorectal cancer prevention.
Cite This Study
Zainab Mohammed Jasim (2025) studied this question.