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Solid dispersions with soluplus improve drug solubility and bioavailability, highlighting their importance.
Many drugs have poor water solubility, which reduces their effectiveness. Solid dispersions are used to enhance the dissolution of such drugs. Soluplus, a polymer, improves drug solubility, prevents crystallization, and enhances absorption. It can be incorporated using techniques such as hot-melt extrusion, spray drying, and solvent evaporation. Incorporating Soluplus in solid dispersions improves drug performance and facilitates better bioavailability.
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K et al. (2025) studied this question.
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