Phytochemical Study of Certain Western Siberian Cinquefoil Species

The total content of phenolic compounds (according to Folinа-Cecalteu), flavonols, catechins, tannins, phenolic acids, as well as saponins was studied and the antiradical activity in extracts from leaves and inflorescences of eight representatives of the genus Potentilla (Rosaceae) - Potentilla supine, P. argentea, P. anserina, P. bifurcate, P. humifusa, P. longifolia, P. multifida, Р. fruticosa, living in Western Siberia. It has been shown that depending on the species, plant organ and habitat, biologically active compounds are synthesized in different ways. According to the higher content of flavonols, tannins and catechins, leaves and inflorescences are distinguished P. argentea, P. anserina, P. bifurcate и Р. fruticosa. Flavonol content in the leaves of these species varies from 5.49% and in inflorescences to 12.33%. By catechol content Р. f ruticosa (up to 1.5%). There was a significant accumulation of tannins in the leaves and inflorescences of the studied plants up to 3.0% in the leaves and up to 3.32% in the inflorescences P. argentea. The least flavonols and tannins accumulate in the leaves of P. multifida compared to other species. A high saponin content was found in leaves of the species P. anserine (34.94%) and P. fruticosa (21.61%) and in inflorescences of P. argentea (26.37%) and P. anserine (26.24%). The minimum value of saponins in the leaves of P. anserine (6.19%) and in the inflorescences of P. multifida (2.97%). Extracts from P. bifurcate leaves (IC50 = 0.37 mg/ml) and inflorescences (IC50 = 0.30 mg/ml) showed higher antiradical activity. Extracts from P. anserine leaves (IC50 = 2.55 mg/ml) and P. argentea inflorescences (IC50 = 3.59 mg/ml) are less effective.