Review highlights microfluidic platforms improving drug delivery effectiveness in precision medicine and reducing side effects.
The quest for precision medicine, individualization and minimal invasiveness, have prompted a change from traditional delivery methods to more intelligent, regulated techniques that improve therapeutic results and reduce adverse effects. In this transition, microfluidic platforms-which can manipulate fluids at the microscale-have become a game-changing answer. Recent developments in lab-on-a-chip (LOC) systems, microneedle-assisted platforms, and drug-carrier-integrated devices are highlighted in this review on microfluidics-enabled drug delivery. Along with important material issues like biocompatibility, chemical resistance and mechanical qualities, this review describes important microfabrication processes including photolithography, soft lithography, and 3D printing. Microfluidic systems have found use in diagnostics, nanomedicine, organ-on-chip models, and paediatric-friendly technologies because of their adaptability. These technologies enable high-throughput, portable and affordable options for point-of-care and customized medicines in addition to providing temporal and geographic control over drug release. Microfluidic-controlled medication delivery has the potential to revolutionize treatment approaches for complicated illnesses in the near future by bridging the gap between engineering and biomedicine.
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Dwivedi et al. (2025) studied this question.
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