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This is a Case Report study (also classified as: Literature Review).

October 3, 2025LifeOpen Access

Antibiotic-Loaded PMMA Beads for Recurrent Sternocutaneous Fistula: Expanding the Surgical Armamentarium in Post-Sternotomy Osteomyelitis: Case Report and Literature Review

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Case report highlights use of antibiotic-impregnated PMMA beads for chronic osteomyelitis, suggesting it may effectively address delayed fistulas.

Local antibiotic delivery using PMMA beads significantly reduces recurrence of chronic sternocutaneous fistulas after surgery.
A 62-year-old patient, treated with antibiotics and surgery, showed no recurrence of fistula after using vancomycin- and gentamicin-loaded PMMA beads.
Combining extensive debridement with PMMA beads can overcome therapeutic challenges in managing late-presenting SCFs.
Suggests a novel approach to expand treatment options for post-sternotomy complications linked to chronic osteomyelitis.

Robu et al. (2025) studied this question.

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Case report highlights use of antibiotic-impregnated PMMA beads for chronic osteomyelitis, suggesting it may effectively address delayed fistulas.