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October 3, 2025

When “Bothered by” Means “Often”: Evidence for Misinterpretation of the Patient Health Questionnaire

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Authors

MPMargarita PanayiotouJRJosip RazumGEGudrun Eisele

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Overview

Analysis reveals misinterpretation of PHQ instructions in community and clinical samples, questioning validity of depression measures.

Key Points

  • Misinterpretation of PHQ instructions raises validity concerns, affecting depression assessment outcomes.
  • Only 54.7% of participants on MTurk interpreted the PHQ correctly when assessing their symptoms and bothersome aspects.
  • Data was collected from a general population sample and a clinical sample, revealing variant interpretations of PHQ instructions.
  • Findings highlight the potential for inaccurate assessments in both research and clinical decision-making based on PHQ validity.

Cite This Study

Panayiotou et al. (2025) studied this question.

synapsesocial.com/papers/68e034fdf0e39f13e7fa34behttps://doi.org/10.31234/osf.io/jcsq8_v3
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