Catalytic asymmetric isomerization/hydroboration of silyl enol ethers

Q: What type of study is this?

This is a Experimental Study study.

Yisen Yao; Jintao Sun; Jie Li; Wanxiang Zhao

doi:10.1039/d5sc04819b

January 1, 2025Chemical ScienceOpen Access

Catalytic asymmetric isomerization/hydroboration of silyl enol ethers

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Key Points

The process yields enantioenriched borylethers effectively under mild conditions, indicating versatility in synthesis.
High functional group tolerance was reported, allowing a wide range of reactive molecules to be used in the reaction.
Catalytic asymmetric isomerization and hydroboration provide efficient pathways to target compounds with value in organic synthesis.
The methodology highlights the potential for broad substrate scope, expanding the utility of silyl enol ethers in synthetic chemistry.

Implication

This synthesis method achieves enantioenriched borylethers from silyl enol ethers, suggesting broad applicability.

Abstract

We report an asymmetric contra-thermodynamic isomerization/hydroboration of silyl enol ethers under mild conditions, enabling efficient access to enantioenriched borylethers with broad substrate scope and good functional group tolerance.

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Cite This Study

Yao et al. (2025) studied this question.

synapsesocial.com/papers/68e24e60d6d66a53c24731aa https://doi.org/10.1039/d5sc04819b

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Catalytic asymmetric isomerization/hydroboration of silyl enol ethers

Key Points

Implication

Abstract

Discussion

Cite This Study

Catalytic asymmetric isomerization/hydroboration of silyl enol ethers

Key Points

Implication

Abstract

Discussion

Cite This Study

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