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October 5, 2025Expert Opinion on Pharmacotherapy4 citations

New and emerging drugs for the treatment of invasive fungal infections

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RMRyan C. MavesMFM. Fowler

Key Points

  • The increase in invasive fungal infections points to a serious global health crisis due to rising prevalence.
  • Approximately 3,800,000 deaths from invasive fungal infections annually primarily result from opportunistic mycoses.
  • Emerging drugs are crucial in managing drug-resistant infections caused by pathogens like Aspergillus and Candida.
  • Growing travel and climate change contribute to higher rates of endemic mycoses, exacerbating existing challenges.

Abstract

Introduction The prevalence of invasive fungal infections (IFI) is increasing globally, with approximately 6,500,000 cases of IFI per year and 3,800,000 deaths. Most IFI deaths are attributable to opportunistic mycoses, such as Aspergillus and Candida. However, changes in climate and travel are leading to rising rates of endemic mycoses. Compounding this burden is the rise of antifungal drug resistance, requiring the development of new agents.

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Cite This Study

Maves et al. (2025) studied this question.

synapsesocial.com/papers/68e28310dcef4a166ce03d37https://doi.org/10.1080/14656566.2025.2568547
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