Metastatic Melanoma of the Ureter Accompanied by Pseudomelanosis Vesica: A Case Report

Less than 1 % of melanomas metastasize to the genitourinary system. Pseudomelanosis is a rare benign condition due to deposition of melanin-like pigment. We present a 44-year-old male with metastatic melanoma to the left ureter accompanied by pseudomelanosis vesica. He had melanoma resected 20 years prior, and was later found to have diffuse metastatic disease. CT abdomen/pelvis found filling defect of the left mid-ureter. Cystourethroscopy showed brown lesions which on biopsy were pseudomelanosis vesica. Subsequently, the ureteral mass was biopsied with results consistent with metastatic melanoma. This case provides insight regarding management of two rare pathologic presentations in the same patient.