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October 3, 2024Organic Letters

Total Synthesis of Rhizopodin Enabled by a Late-Stage Oxazole Ring Formation Strategy

Junyang Liu Kai Chen Yian Guo Ying Chen Tao Ye

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Abstract

Actin stabilizers that are capable of interfering with actin cytoskeleton dynamics play an important role in chemical biology. Rhizopodin, a novel actin stabilizer, affects the actin cytoskeleton at nanomolar concentrations and exhibits potent antiproliferative activities against a range of tumor cell lines with IC

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Cite This Study

Liu et al. (2024) studied this question.

synapsesocial.com/papers/68e55db8e2b3180350efb6b0 https://doi.org/10.1021/acs.orglett.4c03414

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