Molluscum Contagiosum (MC) is an infectious dermatosis disease caused by Molluscum Contagiosum Virus (MCV). MC is treated with mechanical, chemical, immunomodulatory, and antiviral drugs. Predominantly, immunodeficiency HIV-positive patients expressing resistance to MC lesions effectively responded to available drug molecules; therefore, there is a need to develop an effective drug molecule for the treatment of MC infection. Berdazimer topical gel, 10.3% has been developed by Novan Inc. (Ligand Pharmaceuticals) under the brand name Zelsuvmi® for treating MC infection in adult and pediatric patients. Berdazimer topical gel, 10.3% is a Nitric Oxide (NO) releasing topical gel comprising novel NO-based technology platform NITRICI™, which stores gaseous NO species on large polymers.
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Dandekar et al. (2024) studied this question.
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