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September 26, 2024Organic Letters

Selective Synthesis of Mono- and Bis-Phosphorylated (Dihydro)pyrans via TMSCl-Mediated Cascade Phosphorylation Cycloisomerization of Enynones

Yi‐Feng Qiu Qiang Wang Jian-He Cao Dong-Qian Xue Ming Li Zheng‐Jun Quan Xi‐Cun Wang Yong‐Min Liang

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Abstract

A chlorotrimethylsilane (TMSCl)-mediated cascade phosphorylation and cycloisomerization of enynones with diphenylphosphine oxides is presented. This methodology enables the highly selective synthesis of monophosphorylated 2

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Qiu et al. (2024) studied this question.

synapsesocial.com/papers/68e57432b6db64358751476b https://doi.org/10.1021/acs.orglett.4c03397

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