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Surveillance analysis demonstrates high two-dose vaccine effectiveness against mpox in England, indicating strong clinical protection against severe disease.
Reported mpox cases in England continued at a low but steady frequency during 2023. Of 137 cases reported in 2023, approximately half were acquired overseas and half were in vaccinated persons. Estimated effectiveness of 2-dose vaccine was 80%, and no vaccinated mpox patient was hospitalized.
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Charles et al. (2024) studied this question.
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