Scrotal cellular angiofibroma (CAF) is a rare, benign, soft-tissue paratesticular tumor that has been sporadically reported previously. We present a case of a 55-year old male with a scrotal mass ultimately diagnosed with scrotal CAF. Immunohistochemical analysis stained positively for desmin, CD34, and estrogen receptor. Our series is one of the only published to date demonstrating desmin-positive paratesticular CAF. Diagnosis of CAF remains difficult due to the sparsity of paratesticular CAF, its similar characteristics to spindle cell lipoma (SCL), and variability in immunohistochemical reporting.
No takes yet. Share an insight, caveat, or question.
Buchinsky et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: