Background: Presenting advanced breast cancer in Sudan is a significant challenge. Consequently, the objective of this investigation was to evaluate the breast lesion pattern in Western Sudan. Methodology: This study was a retrospective descriptive analysis carried out in two major entities that offer histopathology services in the northern region of Kordofan State. The study encompassed a total of 190 patients, with 110 of them having malignant lesions and 79 having benign breast lesions. Results: Among the 110 cases of breast cancer, 59% were classified as invasive ductal carcinoma (DC), 12.7% as infiltrating DC, and 9% as invasive lobular carcinoma (LC). We identified 37.9% of the 79 non-cancerous growths as fibroadenoma, 25.3% as fibrocystic changes, and 6.3% as Phyllodes tumors. Conclusion: In Sudan, the advanced presentation of breast cancer is common. When a patient presents with a lump, the likelihood of a malignant diagnosis is higher. Breast cancer is a significant concern for younger Sudanese women, particularly those under the age of 45 years.
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