⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

September 20, 2024Journal of Natural ProductsOpen Access

Discovery, Biosynthesis, and Characterization of Rodencin, a Two-Component Lanthipeptide, Harboring d-Amino Acids Introduced by the Unusual Dehydrogenase RodJA

Yuxin Fu Eleftheria Pateri Oscar P. Kuipers

View Full Paper

Ask AI

Bookmark

Share

Abstract

Lanthipeptides, a group of ribosomally synthesized and post-translationally modified peptides (RiPPs), exhibit diverse structures and bioactivities. Their biosynthetic enzymes serve as valuable tools for peptide bioengineering. Here, we report a class II lanthipeptide biosynthetic gene cluster in a

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Fu et al. (2024) studied this question.

synapsesocial.com/papers/68e57d2fb6db64358751bfbb https://doi.org/10.1021/acs.jnatprod.4c00170

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Cell-free biosynthesis and engineering of ribosomally synthesized lanthipeptides2024 · 52 citations
2Discovery and Biosynthesis of Lanthipeptides Featuring an Azepinoindole Scaffold by Radical <i>S</i> -Adenosylmethionine Enzyme-Catalyzed C–C Bond FormationOriginal Research · 2026
3Heterologous Expression Facilitates the Production and Characterization of a Class III Lanthipeptide with Coupled Labionin Cross-Links in Sponge-Associated <i>Streptomyces rochei</i> MB0372024 · 2 citations
4Discovery and Biosynthesis of Dehydroalanine-Containing Lasso Peptide by a Hybrid Biosynthetic System2025 · 4 citations
5Structural Analysis of Class I Lanthipeptides from Pedobacter lusitanus NL19 Reveals an Unusual Ring PatternOriginal Research · 2021 · 40 citations

More related papers

Co-opting the bacterial lipoprotein pathway for the biosynthesis of lipidated macrocyclic peptides2026
Covalent Leader Peptide Probes Reveal Extra-Cluster Enzymes in Ribosomal Peptide Biosynthesis2026
Mining the biosynthetic landscape of lactic acid bacteria unearths a new family of RiPPs assembled by a novel type of ThiF-like adenylyltransferases2024

More from Journal of Natural Products

Acid-Induced Wagner−Meerwein Rearrangements of Lupeol, Betulin, and Betulinic Acid and Synthesis of Allobetulin-Type TriterpenoidsTue,
Cytochalasin H Derivatives from the Marine-Derived Fungus Diaporthe sp. CS−HF−1 and Their Anti-Ferroptotic Activity in Human Proximal Tubular Epithelial CellsTue,