Case Report: Vaginal Melanoma

Vaginal melanoma is extremely rare, accounting for less than 1% of genital melanomas. Its diagnosis is often delayed due to the rarity of specific symptoms. We report the case of a 50-year-old postmenopausal woman who presented with metrorrhagia and a vaginal mass, associated with weight loss. Examination revealed a brownish and hemorrhagic lesion in the vagina, confirmed as vaginal melanoma by biopsy. The melanoma was stage II according to FIGO. The patient underwent a tumorectomy and received adjuvant pelvic and inguinal radiotherapy. After five months, she was deemed in complete remission. Vaginal melanoma, although scarce, requires particular vigilance due to its non-specific symptoms. Treatment is primarily surgical with adjuvant radiotherapy. New therapies such as immunotherapy show promising potential but require further research. Early detection and a multidisciplinary approach are crucial to improving the prognosis of vaginal melanoma. Further research is needed to optimize treatment strategies.