⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

September 18, 2024Oncology Research and Treatment

EGFR-TKI combined with radiotherapy in 105 patients of lung adenocarcinoma with brain metastasis: a retrospective study of prognostic factors analysis

Wenjuan Yu Xing Yuan Xiao Song Tian Li Mi Zhang

View at Publisher

Ask AI

Bookmark

Share

Ask about this paper

Answers are grounded in this paper and cite their sources.

Ask your own question…

Abstract

This study aimed to retrospectively analyze the response and prognosis factors for patients of lung adenocarcinoma with brain metastasis and epidermal growth factor receptor (EGFR) mutation, who were treated by EGFR-tyrosine kinase inhibitor (TKI) combined with brain radiotherapy (RT).

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Yu et al. (2024) studied this question.

synapsesocial.com/papers/68e581e0b6db64358751f0a8 https://doi.org/10.1159/000541494

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1In-depth exploration of the focus issues of TKI combined with radiotherapy for EGFR-mutant lung adenocarcinoma patients with brain metastasis: a systematic analysis based on literature metrology, meta-analysis, and real-world observational dataMeta-Analysis · 2024 · 3 citations
2The efficacy of EGFR-tyrosine kinase inhibitor in non-small cell lung cancer patients with synchronous brain metastasis: a real-world studyRetrospective Study · 2022 · 4 citations
3EGFR-TKI and lung adenocarcinoma with CNS relapse: interest of molecular follow-upOriginal Research · 2009 · 44 citations
4A systematic review and network meta-analysis of first-line EGFR-TKI-based combination strategies for EGFR-mutant non-small cell lung cancer with brain metastasesMeta-Analysis · 2026
5Epidermal growth factor receptor tyrosine kinase inhibitors combined with thoracic radiotherapy or chemoradiotherapy for advanced or metastatic non-small cell lung cancer: A systematic review and meta-analysis of single-arm trialsMeta-Analysis · 2019 · 5 citations

Craniocerebral radiotherapy for EGFR‑mutant non‑small cell lung cancer with brain metastasis: Current evidence and future perspectives on therapeutic strategies (Review)2025
MRI radiomics predicts the efficacy of EGFR-TKI in EGFR-mutant non-small-cell lung cancer with brain metastasis2024
EGFR-TKIs with or without Stereotactic Body Radiotherapy to Primary Lesion in the Advanced EGFR-Mutated Non- Small Cell Lung Cancer2024
The risk of radiotherapy toxicity in patients with laryngeal cancer: predictive factors and radiobiological modellingOncology Research and Treatment · 2026
Case Report: Dose dependent intracranial response to sotorasib in KRASG12C-mutated lung cancer brain metastasesOncology Research and Treatment · 2026

More from Oncology Research and Treatment