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September 16, 2024

Supplementary Figure S2 from CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression

Jordan L. Kohlmeyer Joshua J. Lingo Courtney A. Kaemmer Amanda Scherer Akshaya Warrier Ellen Voigt Juan A. Raygoza Garay Gavin R. McGivney Qierra R. Brockman Amy Tang Ana Calizo Kai Pollard Xiaochun Zhang Angela C. Hirbe Christine A. Pratilas Mariah Leidinger Patrick Breheny Michael S. Chimenti Jessica C. Sieren Varun Monga Munir R. Tanas David K. Meyerholz Benjamin W. Darbro Rebecca D. Dodd Dawn E. Quelle

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Abstract

Supplementary Figure S2. Dual CDK4/6-MEK inhibition synergistically suppresses the growth of some, but not all, MPNST PDXs in immune deficient mice

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Kohlmeyer et al. (2024) studied this question.

synapsesocial.com/papers/68e58589b6db643587522713 https://doi.org/10.1158/1078-0432.27032920

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S2 from CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression2024
2Supplementary Figure S1 from CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression2024
3Supplementary Figure S1 from CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression2024
4Supplementary Figure S8 from CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression2024
5Supplementary Figure S8 from CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression2024

Supplementary Figure S6 from CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression2024
Supplementary Figure S3 from CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression2024
Supplementary Figure S3 from CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression2024