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September 16, 2024

Supplementary Figure S5 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer

Nicole A. Traphagen Gary N. Schwartz Steven Tau Alyssa M. Roberts Amanda Jiang Sarah R. Hosford Jonathan D. Marotti Abigail E. Goen Bianca A. Romo Anneka L. Johnson Emily-Claire K. Duffy Eugene Demidenko Paul Heverly Yaron Mosesson Shannon M. Soucy Fred Kolling Todd W. Miller

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Abstract

Supplementary Figure S5- ER-negative BT-20 cells do not exhibit increased DNA damage upon E2 treatment, while MCF-7/LTED show weak response.

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Traphagen et al. (2024) studied this question.

synapsesocial.com/papers/68e58589b6db643587522756 https://doi.org/10.1158/1078-0432.27033085

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S5 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024
2Supplementary Figure S2 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024
3Supplementary Figure S2 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024
4Supplementary Figure S1 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024
5Supplementary Figure S1 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024

Supplementary Figure S3 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024
Supplementary Figure S4 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024
Supplementary Figure S4 from Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer2024