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September 16, 2024

Figure S3 from S-531011, a novel anti-human CCR8 antibody, induces potent anti-tumor responses through depletion of tumor-infiltrating CCR8-expressing regulatory T cells

Yoji Nagira Morio Nagira Ryohei Nagai Wataru Nogami Michinari Hirata Azumi Ueyama Tetsuya Yoshida M. Yoshikawa Satomi Shinonome Hiroshi Yoshida Miya Haruna Hiroto Miwa Natsumi Chatani Naganari Ohkura Hisashi Wada Hidekazu Tanaka

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Abstract

This is the authors' abstract. We don't add key points for this paper.

Concentration of S-531011 in serum and tumor after a single intravenous administration of S-531011 in CT26.WT tumor-bearing hCCR8 KI mice.

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Cite This Study

Nagira et al. (2024) studied this question.

synapsesocial.com/papers/68e586b5b6db643587522bea https://doi.org/10.1158/1535-7163.27036307.v1

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S5 from S-531011, a novel anti-human CCR8 antibody, induces potent anti-tumor responses through depletion of tumor-infiltrating CCR8-expressing regulatory T cells2024
2Figure S1 from S-531011, a novel anti-human CCR8 antibody, induces potent anti-tumor responses through depletion of tumor-infiltrating CCR8-expressing regulatory T cells2024
3Figure S2 from S-531011, a novel anti-human CCR8 antibody, induces potent anti-tumor responses through depletion of tumor-infiltrating CCR8-expressing regulatory T cells2024
4Figure S4 from S-531011, a novel anti-human CCR8 antibody, induces potent anti-tumor responses through depletion of tumor-infiltrating CCR8-expressing regulatory T cells2024
5Data from S-531011, a novel anti-human CCR8 antibody, induces potent anti-tumor responses through depletion of tumor-infiltrating CCR8-expressing regulatory T cells2024

Supplementary material and method from S-531011, a novel anti-human CCR8 antibody, induces potent anti-tumor responses through depletion of tumor-infiltrating CCR8-expressing regulatory T cells2024
Supplementary material and method from S-531011, a novel anti-human CCR8 antibody, induces potent anti-tumor responses through depletion of tumor-infiltrating CCR8-expressing regulatory T cells2024
Abstract LB130: Identification of fully human CCR8 antibodies that demonstrate excellent ADCC function, potent blocking activity, and robust anti-tumor immune responses2024