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September 16, 2024

Supplemental Figure 2 from Myosin light chain kinase inhibition potentiates the anti-tumor effects of avapritinib in PDGFRA D842V-mutant gastrointestinal stromal tumor

Ferdinand Rossi Mengyuan Liu Andrew Tieniber Mark S. Etherington Andrew Hanna Gerardo A. Vitiello Nesteene J. Param Kevin Do Laura Wang Cristina R. Antonescu Shan Zeng Jennifer Q. Zhang Ronald P. DeMatteo

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Abstract

Supplemental Figure 2. GIST PDGFRA D842V PDXs are not sensitive to imatinib.

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Rossi et al. (2024) studied this question.

synapsesocial.com/papers/68e586b5b6db6435875231d2 https://doi.org/10.1158/1078-0432.27030517

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplemental Figure 2 from Myosin light chain kinase inhibition potentiates the anti-tumor effects of avapritinib in <i>PDGFRA D842V</i>-mutant gastrointestinal stromal tumor2024
2Supplemental Figure 6 from Myosin light chain kinase inhibition potentiates the anti-tumor effects of avapritinib in <i>PDGFRA D842V</i>-mutant gastrointestinal stromal tumor2024
3Supplemental Figure 6 from Myosin light chain kinase inhibition potentiates the anti-tumor effects of avapritinib in <i>PDGFRA D842V</i>-mutant gastrointestinal stromal tumor2024
4Supplemental Figure 3 from Myosin light chain kinase inhibition potentiates the anti-tumor effects of avapritinib in <i>PDGFRA D842V</i>-mutant gastrointestinal stromal tumor2024
5Supplemental Figure 3 from Myosin light chain kinase inhibition potentiates the anti-tumor effects of avapritinib in <i>PDGFRA D842V</i>-mutant gastrointestinal stromal tumor2024

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Supplemental Figure 8 from Myosin light chain kinase inhibition potentiates the anti-tumor effects of avapritinib in <i>PDGFRA D842V</i>-mutant gastrointestinal stromal tumor2024
Supplemental Figure 8 from Myosin light chain kinase inhibition potentiates the anti-tumor effects of avapritinib in <i>PDGFRA D842V</i>-mutant gastrointestinal stromal tumor2024
Supplemental Figure 5 from Myosin light chain kinase inhibition potentiates the anti-tumor effects of avapritinib in <i>PDGFRA D842V</i>-mutant gastrointestinal stromal tumor2024