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September 16, 2024

Supplementary Fig. 6 from Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia

William M. Yashar Brittany M. Curtiss Daniel J. Coleman Jake VanCampen Garth Kong Jommel Macaraeg Joseph Estabrook Emek Demir Nicola Long Daniel Bottomly Shannon K. McWeeney Jeffrey Tyner Brian Druker Julia E. Maxson Theodore P. Braun

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Abstract

Stat5 over-expression diminishes the efficacy of combined FLT3/LSD1 inhibition.

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Yashar et al. (2024) studied this question.

synapsesocial.com/papers/68e586c1b6db643587523824 https://doi.org/10.1158/1541-7786.27034627

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Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Fig. 6 from Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia2024
2Supplementary Fig. 5 from Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia2024
3Supplementary Fig. 5 from Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia2024
4Supplementary Fig. 8 from Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia2024
5Supplementary Fig. 8 from Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia2024
6Supplementary Fig. 4 from Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia2024
7Supplementary Fig. 4 from Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia2024
8Supplementary Fig. 12 from Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia2024