Supplementary Figure S19 from SPOP mutations target STING1 signaling in prostate cancer and create therapeutic vulnerabilities to PARP inhibitor–induced growth suppression

Supplementary Fig. S19. Heatmaps of common differentially expressed genes in co-cultured and mono-cultured prostate cancer model tumor cells demonstrating significant (FDR < 0.05) interaction between treatment [OLA or vehicle control (DMSO)] and SPOP phenotype (RM-1-BM-SPOPF133V mutant–expressing prostate cancer cells w/ or w/o RAW264.7 macrophage cocultured).