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September 16, 2024

Supplemental Figure 4 from Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer

Zannel Blanchard Craig M. Rush Spencer Arnesen Jeffery M. Vahrenkamp Adriana C. Rodriguez Elke A. Jarboe Callie Brown Matthew E.K. Chang Mark R. Flory Hisham Mohammed Katarzyna Modzelewska David H. Lum Jason Gertz

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Abstract

ER mutants do not affect proliferation, but down-regulate proteins associated with movement and impact migration

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Blanchard et al. (2024) studied this question.

synapsesocial.com/papers/68e586c1b6db6435875238f4 https://doi.org/10.1158/1541-7786.27035224.v1

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplemental Figure 4 from Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer2024
2Supplemental Figure 2 from Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer2024
3Supplemental Figure 2 from Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer2024
4Supplemental Figure 7 from Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer2024
5Supplemental Figure 7 from Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer2024

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Supplemental Figure 6 from Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer2024
Supplemental Figure 6 from Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer2024
Supplemental Figure 1 from Allele-specific gene regulation, phenotypes, and therapeutic vulnerabilities in estrogen receptor alpha mutant endometrial cancer2024