Surgical treatment of distant metastases of cutaneous melanoma

This article addresses the question of the effectiveness of surgical treatment for disseminated melanoma. It is shown that disseminated melanoma can be divided into truly disseminated and oligometastatic processes, where distant metastases are resectable. Previously, surgical intervention was the treatment of choice for patients with resectable distant metastases, but with the development of new therapeutic approaches such as immune checkpoint inhibitors and targeted therapies, the role of surgery has become controversial. However, reducing tumor burden through surgical removal of metastatic lesions may enhance the immune response of the body. Combined treatment, involving surgical intervention and systemic therapy, has emerged as a new approach in the treatment of disseminated melanoma, improving efficacy and prognosis for patients. The article emphasizes the need for further research to determine the optimal approach to treating this patient population.