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September 11, 2024MoleculesOpen Access

Computational Exploration of the Mechanism of Action of a Sorafenib-Containing Ruthenium Complex as an Anticancer Agent for Photoactivated Chemotherapy

Pierraffaele Barretta Fortuna Ponte Daniel Escudero Gloria Mazzone

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Abstract

Ruthenium(II) polypyridyl complexes are being tested as potential anticancer agents in different therapies, which include conventional chemotherapy and light-activated approaches. A mechanistic study on a recently synthesized dual-action Ru(II) complex [Ru(bpy)

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Barretta et al. (2024) studied this question.

synapsesocial.com/papers/68e58dd5b6db64358752910e https://doi.org/10.3390/molecules29184298

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