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September 5, 2024ACS Medicinal Chemistry Letters

Design, Synthesis, and Structural Evaluation of Acetylated Phenylthioketone Inhibitors of HDAC10

Juana Goulart Stollmaier P. R. Watson David W. Christianson

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Abstract

Histone deacetylase 10 (HDAC10) is unique among the greater HDAC family due to its unusually narrow substrate specificity as a polyamine deacetylase, specifically as an

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Stollmaier et al. (2024) studied this question.

synapsesocial.com/papers/68e5943fb6db64358752efe2 https://doi.org/10.1021/acsmedchemlett.4c00293

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