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September 4, 2024

Figure S2 from A Next-Generation BRAF Inhibitor Overcomes Resistance to BRAF Inhibition in Patients with BRAF-Mutant Cancers Using Pharmacokinetics-Informed Dose Escalation

Rona Yaeger Meredith McKean Rizwan Haq J. Thaddeus Beck Matthew H. Taylor Jonathan Cohen Daniel W. Bowles Shirish M. Gadgeel Catalin Mihalcioiu Kyriakos P. Papadopoulos Eli L. Diamond Keren Sturtz Gang Feng Stefanie K. Drescher Micaela B. Reddy Bhaswati Sengupta Arnab K. Maity Suzy A. Brown Anurag Singh Eric N. Brown Brian R. Baer Jim Wong Tung‐Chung Mou Wen‐I Wu D Kahn Sunyana Gadal Neal Rosen John J. Gaudino Patrice A. Lee Dylan P. Hartley S. Michael Rothenberg

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Abstract

Figure S2. Crystal structures of BRAF kinase domain with PF-07799933 or encorafenib.

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Cite This Study

Yaeger et al. (2024) studied this question.

synapsesocial.com/papers/68e5968ab6db64358753125b https://doi.org/10.1158/2159-8290.26935065.v1

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S1 from A Next-Generation BRAF Inhibitor Overcomes Resistance to BRAF Inhibition in Patients with <i>BRAF</i>-Mutant Cancers Using Pharmacokinetics-Informed Dose Escalation2024
2Figure S5 from A Next-Generation BRAF Inhibitor Overcomes Resistance to BRAF Inhibition in Patients with <i>BRAF</i>-Mutant Cancers Using Pharmacokinetics-Informed Dose Escalation2024
3Table S2 from A Next-Generation BRAF Inhibitor Overcomes Resistance to BRAF Inhibition in Patients with <i>BRAF</i>-Mutant Cancers Using Pharmacokinetics-Informed Dose Escalation2024
4Table S2 from A Next-Generation BRAF Inhibitor Overcomes Resistance to BRAF Inhibition in Patients with <i>BRAF</i>-Mutant Cancers Using Pharmacokinetics-Informed Dose Escalation2024
5Table S4 from A Next-Generation BRAF Inhibitor Overcomes Resistance to BRAF Inhibition in Patients with <i>BRAF</i>-Mutant Cancers Using Pharmacokinetics-Informed Dose Escalation2024