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September 4, 2024

Supplementary Figure S4 from MYTX-011: A pH-Dependent Anti–c-MET Antibody–Drug Conjugate Designed for Enhanced Payload Delivery to c-MET–Expressing Tumor Cells

Nimish Gera Kyle M. Fitzgerald Vijay Ramesh Purvi Patel Deepak Kanojia Federico Colombo Lena Kien Simon Aoyama Lihui Xu Jussekia Jean Amit M. Deshpande William C. Comb Thomas Chittenden Brian P. Fiske

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Abstract

Total ADC, total mAb and free MMAE levels following a single dose of MYTX-011. Cynomolgus monkeys (n=3 per group) were dosed with 6.0 mg/kg of the respective test articles and total.

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Cite This Study

Gera et al. (2024) studied this question.

synapsesocial.com/papers/68e5969ab6db6435875318fa https://doi.org/10.1158/1535-7163.26934499

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S4 from MYTX-011: A pH-Dependent Anti–c-MET Antibody–Drug Conjugate Designed for Enhanced Payload Delivery to c-MET–Expressing Tumor Cells2024
2Supplementary Figure S3 from MYTX-011: A pH-Dependent Anti–c-MET Antibody–Drug Conjugate Designed for Enhanced Payload Delivery to c-MET–Expressing Tumor Cells2024
3Supplementary Figure S3 from MYTX-011: A pH-Dependent Anti–c-MET Antibody–Drug Conjugate Designed for Enhanced Payload Delivery to c-MET–Expressing Tumor Cells2024
4Supplementary Figure S2 from MYTX-011: A pH-Dependent Anti–c-MET Antibody–Drug Conjugate Designed for Enhanced Payload Delivery to c-MET–Expressing Tumor Cells2024
5Supplementary Figure S2 from MYTX-011: A pH-Dependent Anti–c-MET Antibody–Drug Conjugate Designed for Enhanced Payload Delivery to c-MET–Expressing Tumor Cells2024

More related papers

Supplementary Figure S1 from MYTX-011: A pH-Dependent Anti–c-MET Antibody–Drug Conjugate Designed for Enhanced Payload Delivery to c-MET–Expressing Tumor Cells2024
Supplementary Figure S1 from MYTX-011: A pH-Dependent Anti–c-MET Antibody–Drug Conjugate Designed for Enhanced Payload Delivery to c-MET–Expressing Tumor Cells2024
Data from MYTX-011: A pH-Dependent Anti–c-MET Antibody–Drug Conjugate Designed for Enhanced Payload Delivery to c-MET–Expressing Tumor Cells2024