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September 4, 2024

Figure S9 from HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors

Mary E. Molloy Wade H. Aaron Manasi Barath Mabel C. Bush Evan C. Callihan Kevin Carlin Michael Cremin Thomas Evans Maria G. Guerrero Golzar Hemmati Avneel S. Hundal Llewelyn Lao Payton Laurie Bryan D. Lemon S.J. Lin Jessica O’Rear Purbasa Patnaik Sony Sotelo Rocha Linda Santiago Kathryn L. Strobel Laura B. Valenzuela Chi-Heng Wu Stephen Yu Timothy Z. Yu Banmeet S. Anand Che‐Leung Law Liping L. Sun Holger Wesche Richard J. Austin

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Abstract

HPN328 directs T activation in the presence of DLL3 expressing SHP-77 cells.

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Molloy et al. (2024) studied this question.

synapsesocial.com/papers/68e5969ab6db6435875319b4 https://doi.org/10.1158/1535-7163.26934611.v1

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S3 from HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors2024
2Figure S8 from HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors2024
3Figure S1 from HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors2024
4Figure S16 from HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors2024
5Figure S7 from HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors2024

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Figure S4 from HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors2024
Figure S2 from HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors2024
Figure S10 from HPN328, a Trispecific T Cell–Activating Protein Construct Targeting DLL3-Expressing Solid Tumors2024