Background Oncostatin M (OSM) may be involved in the promotion of mucosal epithelial barrier dysfunction in patients with eosinophilic chronic rhinosinusitis with nasal polyps (Eos CRSwNP) by inducing matrix metalloproteinase (MMP) −1 and −7. The aim was to evaluate the roles and mechanisms of action of OSM on MMP-1 and −7 synthesis from nasal epithelial cells (NECs).
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Wang et al. (2024) studied this question.
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