Enantioselective differentiation of chiral succinate dehydrogenase inhibitor fungicides

Abstract Chiral succinate dehydrogenase inhibitor (SDHI) fungicides have undergone rapid development and extensive application in plant protection. Due to the common existing differences in bioactivity, toxicity, and environmental behavior between the enantiomers of chiral pesticides, a comprehensive evaluation of chiral SDHI fungicides at the enantiomeric level is crucial for gaining a deeper understanding of the behavior of chiral pesticides and facilitating their rational application. This review summarizes the research advancements in analytical methods for chiral SDHI fungicides, and explores enantioselective differences in their bioactivity, toxicity, and enantioselective environmental behavior. These insights are intended to enhance the efficient utilization and risk management of these chiral fungicides.