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September 1, 2024Journal of Inflammation ResearchOpen Access

Molecular Classification of HNSCC Based on Inflammatory Response-Related Genes - Integrated Single-Cell and Bulk RNA-Seq Analysis

Yong Zhu Yongzhe Zhang Xiuli Yu Huaqiang Zhao Chuan Ma

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Abstract

Tumor cells, inflammatory cells, and chemical factors collaboratively orchestrate a sophisticated signaling network, culminating in the formation of the inflammatory tumor microenvironment (TME). The present study sought to explore the nature of the inflammatory response in HNSCC and to decipher its influence on immunotherapeutic.

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Cite This Study

Zhu et al. (2024) studied this question.

synapsesocial.com/papers/68e59fb2b6db64358753a823 https://doi.org/10.2147/jir.s473823

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Deciphering the Heterogeneous Microenvironment of Head and Neck Squamous Cell Carcinoma Through an Integrated Immune Inflammation FrameworkOriginal Research · 2026
2Single-Cell Transcriptomics Identifies Novel Prognostic Signatures in HNSCC Immunotherapy Response.2025
3Integrating scRNA-seq and bulk RNA-seq to characterize immune microenvironment and construct a prognostic model for HNSCCOriginal Research · 2026
4Figure 1 from Inferring Characteristics of the Tumor Immune Microenvironment of Patients with HNSCC from Single-Cell Transcriptomics of Peripheral Blood2024
5Combining Mendelian randomization and multiomics data to determine the causal relationship between systemic inflammation and head and neck squamous cell carcinomaOriginal Research · 2026

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