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August 31, 2024Epilepsy & BehaviorOpen Access

Cognitive outcomes after fetal exposure to carbamazepine, lamotrigine, valproate or levetiracetam monotherapy: Data from the EURAP neurocognitive extension protocol

Susanna Stjerna Yfke Huber‐Mollema Torbjörn Tomson Emilio Perucca Dina Battino John Craig Anne Sabers Sanjeev V. Thomas Frank Vajda Eija Gaily

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Abstract

Prenatal exposure to antiseizure medications (ASMs) has been associated with an increased risk of major malformations and neurodevelopmental disorders, with the latter being mainly associated with valproate (VPA). Our aim was to compare neurocognitive outcome at age 6-7 years in children exposed prenatally to lamotrigine (LTG), carbamazepine (CBZ), valproate (VPA) or levetiracetam (LEV) monotherapy.

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Cite This Study

Stjerna et al. (2024) studied this question.

synapsesocial.com/papers/68e5a0adb6db64358753b71d https://doi.org/10.1016/j.yebeh.2024.110024

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