Symmetrical drug-related intertriginous and flexural erythema is characterized by a diffuse symmetric rash of the gluteal and intertriginous areas with only one published report of association with tamoxifen. It is imperative for clinicians to recognize tamoxifen-induced SDRIFE to avoid life-threatening dermatologic complications, which can be resolved with discontinuation of tamoxifen.
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Hussain et al. (2024) studied this question.
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