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August 26, 2024Biology DirectOpen Access

SUMO3 inhibition by butyric acid suppresses cell viability and glycolysis and promotes gemcitabine antitumor activity in pancreatic cancer

Liming Zhu Gang Chen Changjing Huang Huifeng Gao Yilin Wang Yehua Shen

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Abstract

Excavation of key molecules can help identify therapeutic targets and improve the prognosis of pancreatic cancer. This study evaluated the roles of SUMO3 in cell viability, glycolysis, gemcitabine (GEM) sensitivity, and the antitumor activity of butyric acid (BA) in pancreatic cancer.

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Zhu et al. (2024) studied this question.

synapsesocial.com/papers/68e5adc8b6db643587547686 https://doi.org/10.1186/s13062-024-00513-x

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