Two previously undescribed cationic indole alkaloids, named ophiorrhines L (1) and M (2), was isolated from the Ophiorrhiza japonica.The structures were elucidated based on spectroscopic data and quantum calculations as well as X-ray crystallographic analysis.Alkaloids 1 and 2 exhibited moderate inhibitory activities on XOD (Xanthine Oxidase) with IC50 values 42.5 and 22.6 µM, respectively.
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Shi et al. (2024) studied this question.
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