Clinical and Radiographic Evaluation of Mineral Trioxide Aggregate and Human Amniotic Membrane Pulpotomy in Primary Molars: A Randomized Clinical Trial

also been demonstrated to promote the regeneration of periodontal tissue and maintain its structural and anatomical configuration. 12It has also been demonstrated that the amniotic membrane enhances the healing process following periodontal surgery. 13 IntroductIonPulpotomy is the removal of the inflamed coronal pulp followed by the placement of a suitable material, thereby maintaining healthy radicular pulp and restoring tooth function. 1Historically, many agents have been used in pulpotomy of primary teeth, such as sodium hypochlorite, calcium hydroxide, formocresol, ferric sulfate, and mineral trioxide aggregate (MTA).Studies 2-5 showed that when MTA was utilized as a pulpotomy agent in primary teeth, it outperformed other materials and had a greater success rate.However, disadvantages such as long setting time, discoloration of the tooth, difficult manipulation, and the cost associated with MTA have been fueling the need for newer, effective pulpotomy agents. 4,5he thick foundation membrane and the avascular stromal matrix make up the human amniotic membrane (HAM), also known as the amnion, which is the placenta's deepest layer.Additionally, it is said to lessen discomfort and inflammation, stop infections, and encourage epithelialization. 6The use of HAM isn't new in the health care setting, with HAM being used for the treatment of burned and ulcerated skin surfaces 7,8 as a dural substitute after skull base surgery 9 and in ophthalmology. 10lthough the use of HAM is relatively novel in pediatric dentistry, it has been used in flap surgery and temporomandibular joint surgery because of its pain-reducing and antimicrobial properties.HAM has also been used for ridge preservation following tooth extraction, as a graft material for reconstruction of the buccal mucosa, and as an intraoral dressing material. 8uman amniotic membrane has also been used as a scaffolding material in a wide range of tissue engineering applications 11 and has 1-3,