August 19, 2024Virology Journal11 citationsOpen Access

Bacterial sepsis causes more dramatic pathogenetic changes in the Th1 pathway than does viral (COVID-19) sepsis: a prospective observational study of whole blood transcriptomes

AMArisa MuratsuThe University of Osaka SOSayaka OdaKyoto Municipal Institute of Industrial Technology and Culture SOShinya OnishiJapan Community Healthcare Organization

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Abstract

This study aimed to comprehensively compare host responses of patients with bacterial sepsis and those with viral (COVID-19) sepsis by analyzing messenger RNA (mRNA) and microRNA (miRNA) profiles to shed light on their distinct pathophysiological mechanisms.

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