⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

August 19, 2024AntioxidantsOpen Access

Activation of Nrf2 at Critical Windows of Development Alters Tissue-Specific Protein S-Glutathionylation in the Zebrafish (Danio rerio) Embryo

Emily Marques Emily G. Severance Paige Arsenault Sarah M. Zahn Alicia R. Timme‐Laragy

View Full Paper

Ask AI

Bookmark

Share

Abstract

Activation of Nrf2-the master regulator of antioxidative response-at different stages of embryonic development has been shown to result in changes in gene expression, but the tissue-specific and downstream effects of Nrf2 activation during development remain unclear. This work seeks to elucidate the tissue-specific Nrf2 cellular localization and the downstream changes in protein

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Marques et al. (2024) studied this question.

synapsesocial.com/papers/68e5bb33b6db64358755395a https://doi.org/10.3390/antiox13081006

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Systemic and strict regulation of the glutathione redox state in mitochondria and cytosol is needed for zebrafish ontogeny2024 · 8 citations
2NRF2 regulation in the developing brain cortex from rat offspring exposed to intrauterine and early postnatal zinc deficits2025 · 2 citations
3The role of Nrf2 in thyroid maturation and hormone synthesis in vertebrate modelsOriginal Research · 2026
4Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesitypreclinical · 2010 · 299 citations
5Live Visualization of Endoplasmic Reticulum Redox Potential in Zebrafish Embryos Reveals Region-Specific HeterogeneityOriginal Research · 2026 · 1 citations

More related papers

NRF2 as a guardian of health: from an ancient survival pathway to a modern therapeutic target2026
The role of Nrf2 transcription factors in various physiological and pathological states2024
Regulatory Dynamics of Nrf2 With Sirtuins in the Brain: Exploring Cellular Metabolism, Synaptic Plasticity, and Defense Mechanisms2025

More from Antioxidants

Effects of Empagliflozin on Oxidative Stress in Patients with Obstructive Sleep Apnea and Heart Failure: A Randomized Clinical TrialThu,
Binge Drinking During Adolescence Induces Long-Lasting Oxidative Stress and Inflammation in the Heart and Promotes Cardiac Dysfunction in RatsWed,