In this case report, the potential of pseudoephedrine to induce seizures as a side effect in elderly patients is discussed. Pseudoephedrine is commonly used to relieve nasal congestion caused by allergies, colds, or sinusitis. Still, it has been linked to several side effects, such as cardiovascular events, nervous system toxicity, and drug interactions. The report presents the case of an 83-year-old man with a medical history of diabetes, hypertension, and dyslipidemia who experienced a generalized tonic-clonic seizure after taking an over-the-counter medication containing loratadine and pseudoephedrine. The discussion underscores the need for caution when prescribing pseudoephedrine to elderly patients, particularly those with a history of seizures or other neurological conditions, and recommends alternative treatments like nasal saline irrigation or other decongestants. The case highlights the importance of comprehensive neurological assessment and diagnostic testing in patients with seizures to identify the underlying cause and guide appropriate management. Additional research is necessary to better understand the potential risks and benefits of using pseudoephedrine in elderly patients and explore alternative options for treating nasal congestion.
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Fawzi Mudarres (2024) studied this question.
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