Noomprehensive management of multidrug-resistant bacterial and fungal infections after penetrating chest injury: Treatment of complex postinjury wound infection

Abstract This case report outlines the diagnosis and treatment of a middle-aged male patient who experienced high fall injuries complicated by multidrug-resistant bacterial and fungal infections. The patient sustained a penetrating injury to the right chest, which was accompanied by multiple areas of pain and bleeding. Following emergency surgery and chest drainage, he developed empyema, wound infection, high fever, and multiple organ dysfunction 15 days after the operation, necessitating his transfer from another hospital to our department. Upon admission, we implemented aggressive debridement and multiple vacuum-assisted drainage (VSD) procedures, alongside a comprehensive treatment plan aimed at addressing multidrug-resistant and fungal infections. After 30 days of intensive treatment, the patient experienced significant improvement and was discharged without complications. This case underscores the critical importance of effectively managing complex infections that can arise in the late stages of severe trauma, offering valuable insights for clinicians dealing with similar cases.